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The stresses exerted by the solid components of a tissue and accumulated within solid structural components (i.e., cells, collagen, and hyaluronan) during growth and progression. Solid stress is elevated in tumors because of growth and is independent of the high interstitial fluid pressure. == References== * Jain R.K., "An indirect way to tame cancer", Sci Am 310(2): 46-53, 2014 * Jain R.K., J. D. Martin and T. Stylianopoulos, "The role of mechanical forces in tumor progression and therapy", Annual Reviews of Biomedical Engineering, 16:321-46, 2014. * Jain R.K., "Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers", J Clin Oncol, 31(17):2205-18, 2013. * Stylianopoulos T., J.D. Martin, M. Snuderl, F. Mpekris, S. Jain and R.K. Jain, "Coevolution of solid stress and interstitial fluid pressure in tumor during progression: Implications for vascular collapse", Cancer Research, 73(13): 3833-3841, 2013. * Helmlinger G., P.A. Netti, H. C. Lichtenbeld, R. J. Melder, R. K. Jain, "Solid stress inhibits the growth of multicellular tumor spheroids", Nat Biotechnol 15:778-783, 1997. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Solid stress」の詳細全文を読む スポンサード リンク
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